Estrogen Facilitates Spinal Cord Synaptic Transmission via Membrane-bound Estrogen Receptors
نویسندگان
چکیده
منابع مشابه
Estrogen exerts neuroprotective effects via membrane estrogen receptors and rapid Akt/NOS activation.
The neuroprotective role of estrogen (E2) is supported by a multitude of experimental and epidemiological data, although its mode of action is not fully understood. The present work was conducted to study the underlying mechanisms of its neuroprotective action, using the rat cell line PC12, an established model for neuronal cell apoptosis and survival. Our results show that E2 (but not androgen...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m112.368142